We start the game off in a marketplace, after the opening cinematic follow the little girl to the right and down some steps.
Straight ahead as you go down the steps in the market, make sure to do it before you squeeze through the crowd.
Photo Opportunities are entirely optional for progression through the story but you'll get a Trophy if you manage to snap them all.
Now go through the crowd on the left.
The game's first treasure is impossible to miss as you have to take it back from Meenu.
Aside from this first one Treasures are optional, the only reason to get them is to earn a few Trophies. Just as with all previous Uncharted games the treasures can be seen from afar by their slowly pulsating flash of light.
Continue following the path along heading towards the truck.
As Meenu distracts the soldier move towards the truck and jump in. Hanging around for too long will mean the truck drives off and you have to try again.